Di lain pihak, pelatih Antonio Conte tak mengubah timnya terlalu banyak.
Di lini depan trisula Willian-Eden Hazard-Alvaro Morata masih menjadi andalan.
Danny Drinkwater dimainkan di posisi gelandang tengah menggantikan Cesc Fabregas yang dicadangkan.
Inilah starting XI Man United vs Chelsea:
Manchester United (4-3-3): 1-David de Gea; 25-Antonio Valencia, 12-Chris Smalling, 2-Victor Lindelof, 18-Ashley Young; 31-Nemanja Matic, 6-Paul Pogba, 39-Scott McTominay; 7-Alexis Sanchez, 11-Anthony Martial, 9-Romelu Lukaku.
Cadangan: 3-Eric Bailly, 8-Juan Mata, 14-Jesse Lingard, 16-Michael Carrick, 19-Marcus Rashford, 23-Luke Shaw, 40-Joel Pereira.
Pelatih: Jose Mourinho
Chelsea (3-4-3): 13-Thibaut Courtois; 27-Andreas Christensen, 28-Cesar Azpilicueta, 2-Antonio Ruediger; 3-Marcos Alonso, 7-N'Golo Kante, 6-Danny Drinkwater, 15-Victor Moses; 22-Willian, 10-Eden Hazard, 9-Alvaro Morata.
Cadangan: 1-Willy Caballero, 4-Cesc Fabregas, 11-Pedro Rodriguez, 18-Olivier Giroud, 21-Davide Zappacosta, 24-Gary Cahill, 33-Emerson Palmieri.
Pelatih: Antonio Conte
Stadion: Old Trafford