Dalam pekan pertama, dua tim promosi yakni PSS Sleman dan Kalteng Putra berhasil membuat kejutan setelah kompak meraih kemenangan.
PSS sukses menang 3-1 atas Arema FC dan Kalteng Putra mempermalukan PSIS Semarang dengan skor 2-1.
Berikut klasemen sementara pekan pertama Liga 1 2019:
| Nama Klub | P | M | S | K | +/- | Pts | |
| 1 | Madura United | 1 | 1 | 0 | 0 | 4 | 3 |
| 2 | Persib Bandung | 1 | 1 | 0 | 0 | 3 | 3 |
| 3 | Tira Persikabo | 1 | 1 | 0 | 0 | 3 | 3 |
| 4 | PSS Sleman | 1 | 1 | 0 | 0 | 2 | 3 |
| 5 | Bali United | 1 | 1 | 0 | 0 | 1 | 3 |
| 6 | Kalteng Putra | 1 | 1 | 0 | 0 | 1 | 3 |
| 7 | PSM Makassar | 1 | 1 | 0 | 0 | 1 | 3 |
| 8 | Barito Putera | 1 | 0 | 1 | 0 | 0 | 1 |
| 9 | Bhayangkara FC | 1 | 0 | 1 | 0 | 0 | 1 |
| 10 | Borneo FC | 1 | 0 | 1 | 0 | 0 | 1 |
| 11 | Persija | 1 | 0 | 1 | 0 | 0 | 1 |
| 12 | PSIS Semarang | 1 | 0 | 0 | 0 | -1 | 0 |
| 13 | Persebaya | 1 | 0 | 0 | 1 | -1 | 0 |
| 14 | Semen Padang | 1 | 0 | 0 | 1 | -1 | 0 |
| 15 | Arema FC | 1 | 0 | 0 | 1 | -2 | 0 |
| 16 | Perseru Badak Lampung FC | 1 | 0 | 0 | 1 | -3 | 0 |
| 17 | Persipura Jayapura | 1 | 0 | 0 | 1 | -3 | 0 |
| 18 | Persela Lamongan | 1 | 0 | 0 | 1 | -4 | 0 |