Adapun momen terbaik Messi terjadi pada periode 2008-2010 bersama Barcelona.
Dalam kurun waktu tersebut, Messi memenangi enam final berurutan.
Lalu pada 2011 hingga 2012, dia merasakan kemenangan beruntun di lima partai puncak.
Detail final Messi:
7-2-2005, Piala Dunia U-20, Argentina 2-1 Nigeria
8-17-2006, Piala Super Spanyol, Espanyol 0-1 Barcelona dan 8-20-2006, Barcelona 3-0 Espanyol.
8-25-2006, Piala Super Eropa, Barcelona 0-3 Sevilla
7-15-2007, Copa America, Brazil 3-0 Argentina
8-23-2008, Olimpiade, Argentina 1-0 Nigeria
5-13-2009, Copa del Rey, Athletic Club 1-4 Barcelona
5-27-2009, Liga Champions, Barcelona 2-0 Manchester United
8-23-2009, Piala Super Spanyol, Barcelona 3-0 Athletic Club
8-28-2009, Piala Super Eropa, Barcelona 1-0 Shakhtar
12-19-2009, Piala Dunia Antarklub, Students 1-2 Barcelona
8-14-2010, Piala Super Spanyol, Sevilla 3-1 Barcelona dan 8-21-2010, Barcelona 4-0 Sevilla
4-20-2011, Copa del Rey, Barcelona 0-1 Real Madrid
5-28-2011, Liga Champions, Barcelona 3-1 Manchester United
8-14-2011, Piala Super Spanyol, Real Madrid 2-2 Barcelona dan 8-18-2011, Barcelona 3-2 Real Madrid
8-26-2011, Piala Super Eropa, Barcelona 2-0 Porto
12-18-2011, Piala Dunia Antarklub, Santos 0-4 Barcelona
25-5-2012, Copa del Rey, Athletic Club 0-3 Barcelona
8-23-2012, Piala Super Spanyol, Barcelona 3-2 Real Madrid dan 8-29-2012, Real Madrid 2-1 Barcelona
8-21-2013, Piala Super Spanyol, Atlético de Madrid 1-1 Barcelona dan 8-29-2013, Barcelona 0-0 Atlético de Madrid
4-16-2014, Copa del Rey, Real Madrid 2-1 Barcelona
7-13-2014, Piala Dunia 2014, Jerman 1-0 Argentina
5-30-2015, Copa del Rey, Athletic Club 1-3 Barcelona
6-6-2015, Liga Champions, Juventus 1-3 Barcelona
7-4-2015, Copa America, Chile 0 (4) -0 (1) Argentina
8-11-2015, Piala Super Eropa, Barcelona 5-4 Sevilla
8-14-2015, Piala Super Spanyol, Athletic Club 4-0 Barcelona dan 8-17-2015, Barcelona 1-1 Athletic Club
12-20-2015, Piala Dunia Antarklub, River 0-3 Barcelona
5-22-2016, Copa del Rey, Barcelona 2-0 Sevilla
6-26-2016, Copa America Centenario, Argentina 0 (2) - 0 (4) Chile
8-14-2016, Piala Super Spanyol, Sevilla 0-2 Barcelona dan 8-17-2016, Barcelona 3-0 Sevilla
5-27-2017, Copa del Rey, Barcelona 3-1 Deportivo Alavés
8-13-2017, Piala Super Spanyol, Barcelona 1-3 Real Madrid and 8-16-2017, Real Madrid 2-0 Barcelona
4-21-2018, Copa del Rey, Barcelona 5-0 Sevilla
8-12-2018, Piala Super Spanyol, Barcelona 2-1 Sevilla
5-25-2019, Copa del Rey, Barcelona 1-2 Valencia
01-17-2021, Piala Super Spanyol, Barcelona 2-3 Athletic Club
04-17-2021, Copa del Rey, Athletic Club 0-4 Barcelona
07-10-2021, Copa America, Argentina 1-0 Brazil
06-01-2022, Finalísima, Argentina 3-0 Italy
07-31-2022, Piala Super Prancis, PSG 4-0 Nantes
12-18-2022, Piala Dunia 2022, Argentina 3 (4) -3 (2)
29-8-2023, Leagues Cup, Inter Miami 1 (10) - Nashville 1 (9)