Tak ada gol tambahan sampai peluit akhir dibunyikan. Tiket perempat final jadi milik Milan.
Slavia Praha 1-3 AC Milan (Matj Jurasek 84'; Christian Pulisic 33', Ruben Loftus-Cheek 36', Rafael Leao 45+6')
Slavia Praha: 36-Jindich Stanek, 19-Oscar Dorley, 27-Toma Vicek (29-Michal Tomic 46'), 5-Igoh Ogbu, 33-Ondej Zmrzly, 4-David Zima, 3-Toma Holes, 17-Luka Provod (35-Matj Jurasek 82'), 21-David Doudera (26-Ivan Schranz 82'), 6-Conrad Wallem (10-Chritos Zafeiris 70'), 13-Mojmir Chytil (15-Vaclav Jurecka 59')
Pelatih: Jindich Trpisovsky
AC Milan: 16-Mike Maignan (57-MArco Sportiello 21'), 2-Davide Calabria (20-Pierre Kalulu 46'), 23-Fikayo Tomori (28-Malick Thiaw 46'), 19-Theo Hernandez, 46-Matteo Gabbia, 8-Ruben Loftus-Cheek (14-Tijjani Reijnders 67'), 11-Christian Pulisic (21-Samuel Chukwueze 63'), 7-Yacine Adli, 80-Yunus Musah, 9-Olivier Giroud, 10-Rafael Leao
Pelatih: Stefano Pioli